Custom Peptides
Cayman Chemical 1-Isothiocyanato-6-(methylsulfenyl)-hexane, Purity: ≥98%, CAS: 4430-39-1, 10 mg
An isothiocyanate; active against B. subtilis in an agar diffusion assay at 25 µmol/disc and T. mentagrophytes (MIC = 25 µg/ml); has repellent activity in the blue mussel (M. edulis) assay, as well as antifouling activity in the conventional submerged assay when applied to PVC plates at 50 µmol/cm2
Cayman Chemical (1S,4S)-N-desmethyl Sertraline (hydrochloride), Purity: ≥95%, CAS: 675126-10-0, 10 mg
A metabolite of sertraline; inhibits 5-HT and DA uptake in the rat corpus striatum (IC50s = 0.45 and 3.8 µM, respectively) and NE uptake in the rat hypothalamus (IC50 = 4.6 µM); does not increase extracellular levels of 5-HT or decrease extracellular levels of 5-HIAA in the rat striatum; does not increase cell firing in the rat dorsal raphe at 1,000 µg/kg, i.v.
Cayman Chemical Micheliolide, Purity: ≥98%, CAS: 68370-47-8, 10 mg
A sesquiterpene lactone with diverse biological activities; an irreversible activator of PKM2 (EC50 = 6 nM); decreases viability of HL-60 cells at 5-20 µM; reduces M. tuberculosis-induced secretion of IL-1β and TNF-α, expression of COX-2, and production of NO in RAW 264.7 cells; decreases the severity of CIA in a mouse model of rheumatoid arthritis at 30 mg/kg
Cayman Chemical 4-Aminophenylphosphorylcholine, Purity: ≥95%, CAS: 102185-28-4, 10 mg
A probe that can be conjugated to sepharose in order to generate an adsorbent for use in affinity precipitation experiments
Cayman Chemical 2C-TFM (hydrochloride), Purity: ≥95%, CAS: 159277-13-1, 10 mg
A 2C compound with a para-trifluoromethyl substitution. It is a potent agonist of the 5-HT receptor subtypes 5-HT2A and 5-HT2C (Kaff = 165 and 32 nM); intended for forensic and research purposes
Cayman Chemical N6-Cyclopentyladenosine, Purity: ≥98%, CAS: 41552-82-3, 10 mg
A selective agonist at A1R (Kis = 2.3, 790, and 43 nM for A1R, A2R, and A3R receptors, respectively)
![Cayman Chemical 7-[1-(1H)-Tetrazolylacetamido]desacetoxycephalosporanic Acid, Purity: ≥95%, CAS: 56842-77-4, 10 mg](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502912033.png-250.jpg)
Cayman Chemical 7-[1-(1H)-Tetrazolylacetamido]desacetoxycephalosporanic Acid, Purity: ≥95%, CAS: 56842-77-4, 10 mg
A potential impurity in commercial preparations of cefazolin
Cayman Chemical Dihydrokainic Acid, Purity: ≥95%, CAS: 52497-36-6, 10 mg
An inhibitor of EAAT2 (Ki = 23 µM); selective for EAAT2 over EAAT1 and EAAT3 (Ki = >3 mM for both); reduces depressive-like behavior in rats in the forced swim test at 5 nmol infused into the infralimbic cortex; induces anhedonia-like behavior in rats in a sucrose intake test at 6.25 nmol infused into the PFC; impairs memory acquisition, consolidation, and retrieval in mice in the novel object recognition test
Cayman Chemical PAR41-6mousetrIfluoro 10mg
A peptide PAR4 agonist (EC50 = 30 μM in Xenopus oocytes expressing human PAR4 receptors); corresponds to residues 1-6 of the amino terminal tethered ligand sequence of mouse PAR4 and residues 60-65 of the full-length sequence; induces calcium release in wild-type and PAR3-/- mouse platelets and in human platelets; triggers [3H]inositol phosphate release from KOLF cells expressing human PAR4
Cayman Chemical 5-MAPB (hydrochloride), Purity: ≥98%, CAS: 1823925-53-6, 10 mg
An analytical reference standard categorized as a benzofuran; has been found in seized samples suspected of containing NPS; intended for research and forensic applications
Cayman Chemical Prunin, Purity: ≥98%, CAS: 529-55-5, 10 mg
A flavonoid glycoside with diverse biological activities; inhibits NA activity in oseltamivir-sensitive and -resistant H1N1 influenza strains (IC50s = 3 and 4.53 µM, respectively); scavenges DPPH radicals in a cell-free assay at 2 µM; inhibits the activity of PTP1B (IC50 = 5.5 µM for the human enzyme); increases insulin-induced glucose uptake in insulin-resistant HepG2 cells; inhibits proliferation of, and induces apoptosis in, HL-60 cells
Cayman Chemical 1-(3-Chlorophenyl)piperazine (hydrochloride), Purity: ≥98%, CAS: 13078-15-4, 10 mg
An analytical reference standard categorized as a piperazine; a metabolite of trazodone; has been found in 3,4-MDMA tablets seized by law enforcement; intended for research and forensic applications